rsfS protein (Streptococcus gordonii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

rsfS

Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (121 aa)

Predicted Functional Partners:

SGO_0448

0.975

SGO_0451

0.965

nadD

0.954

SGO_0445

0.944

rpmH

0.924

rplT

0.917

SGO_0446

0.911

rplS

0.911

rpmF

0.909

rplU

0.900

Your Current Organism:

Streptococcus gordonii

NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGO_0445	SGO_0446	SGO_0445	SGO_0446	Identified by match to protein family HMM PF01926.	Conserved hypothetical protein TIGR00253; Identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253.	0.891
SGO_0445	SGO_0448	SGO_0445	SGO_0448	Identified by match to protein family HMM PF01926.	Conserved hypothetical protein TIGR00488; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488.	0.831
SGO_0445	SGO_0451	SGO_0445	SGO_0451	Identified by match to protein family HMM PF01926.	Methyltransferase; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242.	0.693
SGO_0445	nadD	SGO_0445	SGO_0447	Identified by match to protein family HMM PF01926.	Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.860
SGO_0445	rplS	SGO_0445	SGO_1383	Identified by match to protein family HMM PF01926.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.606
SGO_0445	rplT	SGO_0445	SGO_1034	Identified by match to protein family HMM PF01926.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.678
SGO_0445	rplU	SGO_0445	SGO_0818	Identified by match to protein family HMM PF01926.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.747
SGO_0445	rpmF	SGO_0445	SGO_2065	Identified by match to protein family HMM PF01926.	Ribosomal protein L32; Identified by match to protein family HMM PF01783; match to protein family HMM TIGR01031; Belongs to the bacterial ribosomal protein bL32 family.	0.673
SGO_0445	rsfS	SGO_0445	SGO_0450	Identified by match to protein family HMM PF01926.	Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.944
SGO_0446	SGO_0445	SGO_0446	SGO_0445	Conserved hypothetical protein TIGR00253; Identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253.	Identified by match to protein family HMM PF01926.	0.891
SGO_0446	SGO_0448	SGO_0446	SGO_0448	Conserved hypothetical protein TIGR00253; Identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253.	Conserved hypothetical protein TIGR00488; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488.	0.902
SGO_0446	SGO_0451	SGO_0446	SGO_0451	Conserved hypothetical protein TIGR00253; Identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253.	Methyltransferase; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242.	0.846
SGO_0446	nadD	SGO_0446	SGO_0447	Conserved hypothetical protein TIGR00253; Identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253.	Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.945
SGO_0446	rsfS	SGO_0446	SGO_0450	Conserved hypothetical protein TIGR00253; Identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253.	Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.911
SGO_0448	SGO_0445	SGO_0448	SGO_0445	Conserved hypothetical protein TIGR00488; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488.	Identified by match to protein family HMM PF01926.	0.831
SGO_0448	SGO_0446	SGO_0448	SGO_0446	Conserved hypothetical protein TIGR00488; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488.	Conserved hypothetical protein TIGR00253; Identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253.	0.902
SGO_0448	SGO_0451	SGO_0448	SGO_0451	Conserved hypothetical protein TIGR00488; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488.	Methyltransferase; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242.	0.866
SGO_0448	nadD	SGO_0448	SGO_0447	Conserved hypothetical protein TIGR00488; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488.	Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.998
SGO_0448	rsfS	SGO_0448	SGO_0450	Conserved hypothetical protein TIGR00488; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488.	Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.975
SGO_0451	SGO_0445	SGO_0451	SGO_0445	Methyltransferase; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242.	Identified by match to protein family HMM PF01926.	0.693

page 1 of 4

Server load: low (12%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About