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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0492Identified by match to protein family HMM PF07690. (429 aa)    
Predicted Functional Partners:
SGO_0493
Transcriptional regulator, TetR family, putative; Identified by match to protein family HMM PF00440.
 
     0.898
SGO_0883
Transporter, probable SP1116; Identified by match to protein family HMM PF07690.
 
     0.738
dltA
D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]
 
 
  
 0.678
gidB
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
       0.559
SGO_0827
Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.
  
  
 0.487
lemA
Identified by match to protein family HMM PF04011.
  
  
 0.483
htpx
Heat shock protein; Identified by match to protein family HMM PF01435; Belongs to the peptidase M48B family.
     
 0.483
SGO_1878
Transcriptional regulator, TetR family domain protein; Identified by match to protein family HMM PF00440.
  
     0.462
SGO_1074
Conserved hypothetical protein; Identified by match to protein family HMM PF02558.
 
     0.433
SGO_1825
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
  
  
 0.405
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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