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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0493Transcriptional regulator, TetR family, putative; Identified by match to protein family HMM PF00440. (200 aa)    
Predicted Functional Partners:
SGO_0492
Identified by match to protein family HMM PF07690.
 
     0.898
SGO_1878
Transcriptional regulator, TetR family domain protein; Identified by match to protein family HMM PF00440.
  
     0.762
SGO_1287
Putative transcriptional regulator (TetR/AcrR family); Identified by match to protein family HMM PF00440.
  
     0.551
gidB
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
       0.548
htpx
Heat shock protein; Identified by match to protein family HMM PF01435; Belongs to the peptidase M48B family.
  
    0.483
lemA
Identified by match to protein family HMM PF04011.
       0.482
SGO_1876
Uncharacterized membrane protein, putative.
 
     0.444
SGO_1492
Transcription regulator (TetR/AcrR family) BH0580, putative; Identified by match to protein family HMM PF00440.
  
     0.439
SGO_0397
Conserved hypothetical protein.
  
     0.428
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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