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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0509Replication initiation and membrane attachment protein (DnaB) superfamily; Identified by match to protein family HMM PF07261. (384 aa)    
Predicted Functional Partners:
dnaI
Primosomal protein DnaI; Identified by match to protein family HMM PF07319.
 
  
 0.885
nrdR
Transcriptional regulator, NrdR family; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
  
  
 0.872
SGO_0511
NADPH-flavin oxidoreductase -like protein; Identified by match to protein family HMM PF00881; Belongs to the flavin oxidoreductase frp family.
       0.800
SGO_1026
Rhamnosyltransferase; Identified by match to protein family HMM PF05045.
  
     0.715
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
       0.677
SGO_0757
Peptidase, U32 family; Identified by match to protein family HMM PF01183.
  
     0.659
SGO_1672
Recombinase, site specific; Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site. Belongs to the 'phage' integrase family. XerD-like subfamily.
  
     0.619
rexB
Putative exonuclease RexB; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity; Belongs to the helicase family. AddB/RexB type 2 subfamily.
  
     0.586
SGO_0852
TPR domain protein; Identified by similarity to GB:AAO81340.1; match to protein family HMM PF00515.
  
     0.580
adcR
Repressor protein adcR; Identified by match to protein family HMM PF01022; match to protein family HMM PF01047.
  
     0.576
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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