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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0522Acylphosphatase; Identified by match to protein family HMM PF00708. (92 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651.
    
 0.922
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.911
spxB
Pyruvate oxidase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720; Belongs to the TPP enzyme family.
     
  0.900
SGO_0524
HD domain protein; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277.
     
 0.790
yidC-2
Membrane protein oxaA 2 precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
  
    0.637
SGO_0523
spoU rRNA Methylase family protein; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.609
dgkA
Diacylglycerol kinase (DAGK) (Diglyceride kinase)(DGK); Identified by match to protein family HMM PF01219.
     
 0.606
SGO_0703
Ferric transport regulator protein; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
  
  
 0.601
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.599
SGO_1657
Identified by match to protein family HMM PF01594.
     
 0.588
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.