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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbp2XPenicillin-binding protein 2X; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. (751 aa)    
Predicted Functional Partners:
pbp1a
Penicillin-binding protein 1A; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074.
 
 
 0.993
pbp1b
Penicillin-binding protein 1B; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912.
 
 
 0.988
pbp2a
Penicillin-binding protein 2A; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074.
 
 
0.976
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.968
pbp3
Penicillin-binding protein 3; Identified by match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family.
  
 
 0.964
FtsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
  
 
 0.954
mraW
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
  
 0.952
pbp2b
Penicillin-binding protein 2B; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717.
  
  
0.949
SGO_0759
Cell division protein FtsW; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.
 
 0.935
SGO_0843
Carboxypeptidase; Identified by match to protein family HMM PF02557.
  
 
 0.917
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.