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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepCIdentified by match to protein family HMM PF03051; Belongs to the peptidase C1 family. (444 aa)    
Predicted Functional Partners:
SGO_1799
Identified by match to protein family HMM PF01431; match to protein family HMM PF05649.
  
   
 0.793
pepX
X-Pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
  
   
 0.711
folE
GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.
      
 0.641
SGO_0584
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
  
    0.586
rgpA
Rhamnosyltransferase, putative; Identified by match to protein family HMM PF09314.
   
  
 0.582
rnz
Metallo-beta-lactamase superfamily protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
      
 0.579
SGO_0348
Reductase.
      
 0.573
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
     
 0.527
SGO_0582
Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
       0.521
mutL
DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
      
 0.463
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.