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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0588Conserved hypothetical protein; Identified by match to protein family HMM PF06908; Belongs to the UPF0398 family. (175 aa)    
Predicted Functional Partners:
SGO_0852
TPR domain protein; Identified by similarity to GB:AAO81340.1; match to protein family HMM PF00515.
  
     0.748
SGO_0539
ABC transporter, permease protein; Identified by match to protein family HMM PF05975.
  
     0.728
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
    0.716
SGO_1917
Conserved hypothetical protein.
  
     0.669
gpsB
Methylase; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
     
 0.642
pbp1a
Penicillin-binding protein 1A; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074.
       0.610
DivIB
Cell division protein DivIB; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
     0.590
SGO_0793
Conserved hypothetical protein; Identified by match to protein family HMM PF03926; Belongs to the SprT family.
  
     0.566
SGO_1377
Sulfatase; Identified by match to protein family HMM PF00884.
  
     0.529
SGO_0509
Replication initiation and membrane attachment protein (DnaB) superfamily; Identified by match to protein family HMM PF07261.
  
     0.478
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.