| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_1261 | apt | SGO_1261 | SGO_1001 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.918 |
| SGO_1261 | gmk | SGO_1261 | SGO_0594 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.916 |
| SGO_1261 | guaA | SGO_1261 | SGO_1120 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.906 |
| SGO_1261 | guaC | SGO_1261 | SGO_1159 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.948 |
| SGO_1261 | hpt | SGO_1261 | SGO_2134 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.917 |
| SGO_1261 | xpt | SGO_1261 | SGO_1158 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.918 |
| apt | SGO_1261 | SGO_1001 | SGO_1261 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | 0.918 |
| apt | gmk | SGO_1001 | SGO_0594 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.943 |
| apt | guaA | SGO_1001 | SGO_1120 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.984 |
| apt | guaC | SGO_1001 | SGO_1159 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.922 |
| apt | hpt | SGO_1001 | SGO_2134 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.970 |
| apt | xpt | SGO_1001 | SGO_1158 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.967 |
| gmk | SGO_1261 | SGO_0594 | SGO_1261 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | 0.916 |
| gmk | apt | SGO_0594 | SGO_1001 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.943 |
| gmk | guaA | SGO_0594 | SGO_1120 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.964 |
| gmk | guaC | SGO_0594 | SGO_1159 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.914 |
| gmk | hpt | SGO_0594 | SGO_2134 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.927 |
| gmk | nrdE | SGO_0594 | SGO_1558 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.914 |
| gmk | pyk | SGO_0594 | SGO_1339 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.932 |
| gmk | relA | SGO_0594 | SGO_1822 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.927 |
STRING v12.5 is now available!
