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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0602Histidine kinase; Identified by match to protein family HMM PF02518; match to protein family HMM PF07730. (317 aa)    
Predicted Functional Partners:
SGO_0603
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281.
 
 0.997
SGO_0601
Conserved hypothetical protein.
 
  
 0.926
SGO_1895
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.
 
 
 0.896
SGO_1731
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281.
 
 
 0.894
SGO_0600
Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; match to protein family HMM PF03793.
  
  
 0.665
SGO_0604
Hydrolase, haloacid dehalogenase family/peptidyl-prolyl cis-trans isomerase, cyclophilin type; Identified by match to protein family HMM PF00160; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484.
  
    0.601
SGO_0605
General stress protein GSP13; Identified by match to protein family HMM PF00575.
       0.597
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.524
SGO_1398
Conserved domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF03061; match to protein family HMM PF07085.
  
     0.517
SGO_0734
PspC domain protein; Identified by match to protein family HMM PF04024.
  
  
 0.471
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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