close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comFCCompetence protein ComFC. (221 aa)    
Predicted Functional Partners:
comFA
Competence ComFA-like protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
 
  
 0.971
celB
DNA internalization-related competence protein celB; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.
 
  
 0.784
SGO_1198
DNA processing Smf protein; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732.
 
 
 0.781
comYA
Competence protein comYA; Identified by match to protein family HMM PF00437.
  
  
 0.765
SGO_1229
DNA repair protein; Identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
 
    0.683
SGO_0607
Conserved hypothetical protein TIGR00257; Identified by match to protein family HMM PF01205; match to protein family HMM TIGR00257.
  
    0.626
hpf
Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
    0.612
SGO_1371
Prephenate dehydrogenase; Identified by match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.
   
  
 0.552
nagA
N-acetylglucosamine-6-phosphate deacetylase; Identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221.
  
    0.543
celA
Competence protein CelA; Identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426.
  
  
 0.540
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.