node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SGO_0658 | pabB | SGO_0658 | SGO_0307 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 0.999 |
SGO_0658 | trpA-1 | SGO_0658 | SGO_0424 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Tryptophan synthase, alpha subunit; Identified by match to protein family HMM PF00290; match to protein family HMM TIGR00262. | 0.906 |
SGO_0658 | trpA-2 | SGO_0658 | SGO_0663 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.975 |
SGO_0658 | trpB-1 | SGO_0658 | SGO_0662 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.930 |
SGO_0658 | trpB-2 | SGO_0658 | SGO_0656 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.726 |
SGO_0658 | trpC | SGO_0658 | SGO_0660 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. | 0.999 |
SGO_0658 | trpD | SGO_0658 | SGO_0659 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SGO_0658 | trpE | SGO_0658 | SGO_0657 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
SGO_0658 | trpF | SGO_0658 | SGO_0661 | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.998 |
pabB | SGO_0658 | SGO_0307 | SGO_0658 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.999 |
pabB | topA | SGO_0307 | SGO_1197 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.457 |
pabB | trpA-1 | SGO_0307 | SGO_0424 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Tryptophan synthase, alpha subunit; Identified by match to protein family HMM PF00290; match to protein family HMM TIGR00262. | 0.899 |
pabB | trpA-2 | SGO_0307 | SGO_0663 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.887 |
pabB | trpB-1 | SGO_0307 | SGO_0662 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.840 |
pabB | trpB-2 | SGO_0307 | SGO_0656 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.840 |
pabB | trpC | SGO_0307 | SGO_0660 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. | 0.983 |
pabB | trpD | SGO_0307 | SGO_0659 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.995 |
pabB | trpE | SGO_0307 | SGO_0657 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.875 |
pabB | trpF | SGO_0307 | SGO_0661 | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.854 |
topA | pabB | SGO_1197 | SGO_0307 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 0.457 |