| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_0700 | hup | SGO_0700 | SGO_0701 | Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762. | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.565 |
| SGO_0702 | SGO_1695 | SGO_0702 | SGO_1695 | Conserved hypothetical protein. | Enoyl-acyl carrier protein(ACP) reductase; Identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151. | 0.624 |
| SGO_0702 | hup | SGO_0702 | SGO_0701 | Conserved hypothetical protein. | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.627 |
| SGO_0702 | pyrB | SGO_0702 | SGO_1109 | Conserved hypothetical protein. | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.624 |
| SGO_1695 | SGO_0702 | SGO_1695 | SGO_0702 | Enoyl-acyl carrier protein(ACP) reductase; Identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151. | Conserved hypothetical protein. | 0.624 |
| SGO_1695 | hup | SGO_1695 | SGO_0701 | Enoyl-acyl carrier protein(ACP) reductase; Identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151. | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.624 |
| SGO_1695 | pyrB | SGO_1695 | SGO_1109 | Enoyl-acyl carrier protein(ACP) reductase; Identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151. | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.627 |
| cas1 | hup | SGO_1380 | SGO_0701 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.547 |
| hup | SGO_0700 | SGO_0701 | SGO_0700 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762. | 0.565 |
| hup | SGO_0702 | SGO_0701 | SGO_0702 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Conserved hypothetical protein. | 0.627 |
| hup | SGO_1695 | SGO_0701 | SGO_1695 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Enoyl-acyl carrier protein(ACP) reductase; Identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151. | 0.624 |
| hup | cas1 | SGO_0701 | SGO_1380 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.547 |
| hup | metG | SGO_0701 | SGO_1530 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.623 |
| hup | polI | SGO_0701 | SGO_0145 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.583 |
| hup | pyrB | SGO_0701 | SGO_1109 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.627 |
| hup | rplL | SGO_0701 | SGO_1191 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.547 |
| hup | rpsT | SGO_0701 | SGO_1076 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.591 |
| hup | topA | SGO_0701 | SGO_1197 | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.719 |
| metG | hup | SGO_1530 | SGO_0701 | methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | DNA-binding histone-like protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.623 |
| metG | polI | SGO_1530 | SGO_0145 | methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.815 |
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