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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0730Identified by match to protein family HMM PF00149. (282 aa)    
Predicted Functional Partners:
SGO_0731
Identified by match to protein family HMM PF02082.
  
    0.655
SGO_1839
Conserved hypothetical protein.
    
 
 0.568
SGO_0729
ABC transporter permease protein; Identified by match to protein family HMM PF02687.
  
    0.562
SGO_0728
ABC transporter, ATP-binding protein SP1653; Identified by match to protein family HMM PF00005.
  
    0.561
endA
DNA-entry nuclease; Identified by match to protein family HMM PF01223.
  
     0.507
SGO_1675
HAM1 protein-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.501
SGO_0726
Putative transcriptional regulator TetR/AcrR family; Identified by match to protein family HMM PF00440.
 
     0.462
SGO_0689
Conserved hypothetical protein; Identified by match to protein family HMM PF08796.
  
     0.443
SGO_1124
Cell surface hydrolase; Identified by match to protein family HMM PF06028.
 
     0.421
SGO_0261
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
  
     0.407
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.