| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_0600 | fruA | SGO_0600 | SGO_1113 | Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; match to protein family HMM PF03793. | PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427. | 0.565 |
| SGO_0600 | hprK | SGO_0600 | SGO_0736 | Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; match to protein family HMM PF03793. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.750 |
| SGO_0600 | lgt | SGO_0600 | SGO_0737 | Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; match to protein family HMM PF03793. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.571 |
| SGO_0738 | SGO_0739 | SGO_0738 | SGO_0739 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | Conserved hypothetical protein. | 0.844 |
| SGO_0738 | hprK | SGO_0738 | SGO_0736 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.800 |
| SGO_0738 | lgt | SGO_0738 | SGO_0737 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.800 |
| SGO_0739 | SGO_0738 | SGO_0739 | SGO_0738 | Conserved hypothetical protein. | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | 0.844 |
| SGO_0739 | hprK | SGO_0739 | SGO_0736 | Conserved hypothetical protein. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.740 |
| SGO_0739 | lgt | SGO_0739 | SGO_0737 | Conserved hypothetical protein. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.740 |
| SGO_1556 | fruA | SGO_1556 | SGO_1113 | Phosphocarrier protein HPr; Identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003. | PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427. | 0.996 |
| SGO_1556 | hprK | SGO_1556 | SGO_0736 | Phosphocarrier protein HPr; Identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.835 |
| SGO_1556 | ptsI | SGO_1556 | SGO_1555 | Phosphocarrier protein HPr; Identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003. | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.999 |
| SGO_1788 | hprK | SGO_1788 | SGO_0736 | Pyruvate formate-lyase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.602 |
| fruA | SGO_0600 | SGO_1113 | SGO_0600 | PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427. | Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; match to protein family HMM PF03793. | 0.565 |
| fruA | SGO_1556 | SGO_1113 | SGO_1556 | PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427. | Phosphocarrier protein HPr; Identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003. | 0.996 |
| fruA | hprK | SGO_1113 | SGO_0736 | PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.664 |
| fruA | nagB | SGO_1113 | SGO_1586 | PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.483 |
| fruA | ptsI | SGO_1113 | SGO_1555 | PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427. | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.990 |
| hprK | SGO_0600 | SGO_0736 | SGO_0600 | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; match to protein family HMM PF03793. | 0.750 |
| hprK | SGO_0738 | SGO_0736 | SGO_0738 | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | 0.800 |