| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EzrA | SGO_0738 | SGO_1431 | SGO_0738 | Septation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | 0.529 |
| EzrA | mecA | SGO_1431 | SGO_1724 | Septation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Adapter protein mec; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. | 0.755 |
| EzrA | rpoE | SGO_1431 | SGO_0413 | Septation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | DNA-directed RNA polymerase delta chain; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.701 |
| EzrA | rpoZ | SGO_1431 | SGO_0595 | Septation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.570 |
| SGO_0021 | SGO_0738 | SGO_0021 | SGO_0738 | Conserved domain protein; Identified by match to protein family HMM PF01476. | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | 0.543 |
| SGO_0738 | EzrA | SGO_0738 | SGO_1431 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | Septation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.529 |
| SGO_0738 | SGO_0021 | SGO_0738 | SGO_0021 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | Conserved domain protein; Identified by match to protein family HMM PF01476. | 0.543 |
| SGO_0738 | SGO_0739 | SGO_0738 | SGO_0739 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | Conserved hypothetical protein. | 0.844 |
| SGO_0738 | SGO_1673 | SGO_0738 | SGO_1673 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | CBS domain protein; Identified by match to protein family HMM PF00571. | 0.577 |
| SGO_0738 | hprK | SGO_0738 | SGO_0736 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.800 |
| SGO_0738 | lgt | SGO_0738 | SGO_0737 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.800 |
| SGO_0738 | mecA | SGO_0738 | SGO_1724 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | Adapter protein mec; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. | 0.517 |
| SGO_0738 | rpoE | SGO_0738 | SGO_0413 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | DNA-directed RNA polymerase delta chain; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.730 |
| SGO_0738 | rpoZ | SGO_0738 | SGO_0595 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.611 |
| SGO_0738 | spxA | SGO_0738 | SGO_1051 | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | Negative regulator of proteolysis; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.505 |
| SGO_0739 | SGO_0738 | SGO_0739 | SGO_0738 | Conserved hypothetical protein. | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | 0.844 |
| SGO_0739 | hprK | SGO_0739 | SGO_0736 | Conserved hypothetical protein. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.740 |
| SGO_0739 | lgt | SGO_0739 | SGO_0737 | Conserved hypothetical protein. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.740 |
| SGO_1673 | SGO_0738 | SGO_1673 | SGO_0738 | CBS domain protein; Identified by match to protein family HMM PF00571. | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | 0.577 |
| hprK | SGO_0738 | SGO_0736 | SGO_0738 | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | Bacterial protein of unknown function (DUF948) family; Identified by match to protein family HMM PF06103. | 0.800 |