Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SGO_0749Glutathione reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01421. (449 aa)    
Predicted Functional Partners:
SGO_0758
Glutathione peroxidase; Identified by match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
  
 0.963
sucB
Dihydrolipoamide S-acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF02817.
 0.901
SGO_1132
Acetoin dehydrogenase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.
 
 0.823
tpx
Thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
   
  
 0.791
SGO_1130
Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
 
0.788
gshAB
Glutamate--cysteine ligase, putative/amino acid ligase, putative; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
  
   
 0.754
SGO_0751
ABC transporter, ATP-binding protein SP0786; Identified by match to protein family HMM PF00005.
       0.707
SGO_0752
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF02687.
       0.707
SGO_1069
Membrane alanyl aminopeptidase; Identified by match to protein family HMM PF01433.
   
 
 0.606
SGO_0372
Malate oxidoreductase; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.
  
 
 0.601
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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