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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0780Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229. (453 aa)    
Predicted Functional Partners:
SGO_0779
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 0.997
SGO_1181
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 0.849
SGO_1417
Response regulator protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 0.838
SGO_1908
DNA response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 0.835
SGO_0298
Two-component response regulator, putative; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 0.832
vicX
Zn-dependent hydrolase (beta-lactamase superfamily); Identified by match to protein family HMM PF00753.
  
  
 0.830
SGO_0485
DNA-binding response regulator; Identified by match to protein family HMM PF00072.
 
 0.788
SGO_1175
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00165.
 
   
 0.780
SGO_1505
Response regulator Rr1; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 0.774
ciaR
Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 0.744
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.