thiI protein (Streptococcus gordonii) - STRING interaction network

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thiI

Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (404 aa)

Predicted Functional Partners:

SGO_0814

0.992

SGO_1225

0.963

sun

0.886

SGO_0816

0.724

guaA

0.623

rpsE

0.595

hlyIII

0.587

SGO_0819

0.560

celB

0.551

fbp

0.547

Your Current Organism:

Streptococcus gordonii

NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGO_0814	SGO_0816	SGO_0814	SGO_0816	Aminotransferase, class-V; Identified by match to protein family HMM PF00266.	Conserved hypothetical protein.	0.731
SGO_0814	SGO_1225	SGO_0814	SGO_1225	Aminotransferase, class-V; Identified by match to protein family HMM PF00266.	Pyridoxal-phosphate dependent aminotransferase; Identified by match to protein family HMM PF00266.	0.915
SGO_0814	fbp	SGO_0814	SGO_0813	Aminotransferase, class-V; Identified by match to protein family HMM PF00266.	Fructose-bisphosphatase; Identified by match to protein family HMM PF06874.	0.542
SGO_0814	thiI	SGO_0814	SGO_0815	Aminotransferase, class-V; Identified by match to protein family HMM PF00266.	Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.992
SGO_0816	SGO_0814	SGO_0816	SGO_0814	Conserved hypothetical protein.	Aminotransferase, class-V; Identified by match to protein family HMM PF00266.	0.731
SGO_0816	celB	SGO_0816	SGO_1601	Conserved hypothetical protein.	DNA internalization-related competence protein celB; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.	0.403
SGO_0816	fbp	SGO_0816	SGO_0813	Conserved hypothetical protein.	Fructose-bisphosphatase; Identified by match to protein family HMM PF06874.	0.488
SGO_0816	thiI	SGO_0816	SGO_0815	Conserved hypothetical protein.	Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.724
SGO_0819	thiI	SGO_0819	SGO_0815	Identified by match to protein family HMM PF04327.	Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.560
SGO_1225	SGO_0814	SGO_1225	SGO_0814	Pyridoxal-phosphate dependent aminotransferase; Identified by match to protein family HMM PF00266.	Aminotransferase, class-V; Identified by match to protein family HMM PF00266.	0.915
SGO_1225	thiI	SGO_1225	SGO_0815	Pyridoxal-phosphate dependent aminotransferase; Identified by match to protein family HMM PF00266.	Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.963
celB	SGO_0816	SGO_1601	SGO_0816	DNA internalization-related competence protein celB; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.	Conserved hypothetical protein.	0.403
celB	guaA	SGO_1601	SGO_1120	DNA internalization-related competence protein celB; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.414
celB	thiI	SGO_1601	SGO_0815	DNA internalization-related competence protein celB; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.	Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.551
fbp	SGO_0814	SGO_0813	SGO_0814	Fructose-bisphosphatase; Identified by match to protein family HMM PF06874.	Aminotransferase, class-V; Identified by match to protein family HMM PF00266.	0.542
fbp	SGO_0816	SGO_0813	SGO_0816	Fructose-bisphosphatase; Identified by match to protein family HMM PF06874.	Conserved hypothetical protein.	0.488
fbp	thiI	SGO_0813	SGO_0815	Fructose-bisphosphatase; Identified by match to protein family HMM PF06874.	Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.547
guaA	celB	SGO_1120	SGO_1601	GMP synthase; Catalyzes the synthesis of GMP from XMP.	DNA internalization-related competence protein celB; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.	0.414
guaA	hlyIII	SGO_1120	SGO_1309	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Hemolysin III-like protein; Identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065.	0.400
guaA	rpsE	SGO_1120	SGO_1968	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	0.753

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