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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0844Conserved hypothetical protein. (96 aa)    
Predicted Functional Partners:
SGO_0843
Carboxypeptidase; Identified by match to protein family HMM PF02557.
       0.590
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.516
SGO_0842
Identified by match to protein family HMM PF00581.
  
    0.479
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.456
cobB
NAD-dependent deacetylase (Regulatory protein SIR2-like protein); NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
    0.452
SGO_0042
Transcription regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.
  
    0.450
SGO_1121
Transcription regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.
  
    0.450
SGO_1654
Trehalose operon transcription repressor; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404.
  
    0.450
SGO_0841
Oxidoreductase; Identified by match to protein family HMM PF08240.
  
  
 0.439
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
    0.438
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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