| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_0908 | SGO_0911 | SGO_0908 | SGO_0911 | Predicted membrane protein of unknown function (DUF1294); Identified by match to protein family HMM PF06961. | Conserved hypothetical protein; Belongs to the SUA5 family. | 0.722 |
| SGO_0908 | leuA | SGO_0908 | SGO_0906 | Predicted membrane protein of unknown function (DUF1294); Identified by match to protein family HMM PF06961. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.866 |
| SGO_0908 | leuB | SGO_0908 | SGO_0907 | Predicted membrane protein of unknown function (DUF1294); Identified by match to protein family HMM PF06961. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.885 |
| SGO_0908 | leuC | SGO_0908 | SGO_0909 | Predicted membrane protein of unknown function (DUF1294); Identified by match to protein family HMM PF06961. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.863 |
| SGO_0908 | leuD | SGO_0908 | SGO_0910 | Predicted membrane protein of unknown function (DUF1294); Identified by match to protein family HMM PF06961. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.857 |
| SGO_0911 | SGO_0908 | SGO_0911 | SGO_0908 | Conserved hypothetical protein; Belongs to the SUA5 family. | Predicted membrane protein of unknown function (DUF1294); Identified by match to protein family HMM PF06961. | 0.722 |
| SGO_0911 | SGO_0912 | SGO_0911 | SGO_0912 | Conserved hypothetical protein; Belongs to the SUA5 family. | Identified by match to protein family HMM PF01047. | 0.437 |
| SGO_0911 | leuA | SGO_0911 | SGO_0906 | Conserved hypothetical protein; Belongs to the SUA5 family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.719 |
| SGO_0911 | leuB | SGO_0911 | SGO_0907 | Conserved hypothetical protein; Belongs to the SUA5 family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.768 |
| SGO_0911 | leuC | SGO_0911 | SGO_0909 | Conserved hypothetical protein; Belongs to the SUA5 family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.759 |
| SGO_0911 | leuD | SGO_0911 | SGO_0910 | Conserved hypothetical protein; Belongs to the SUA5 family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.777 |
| SGO_0912 | SGO_0911 | SGO_0912 | SGO_0911 | Identified by match to protein family HMM PF01047. | Conserved hypothetical protein; Belongs to the SUA5 family. | 0.437 |
| leuA | SGO_0908 | SGO_0906 | SGO_0908 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Predicted membrane protein of unknown function (DUF1294); Identified by match to protein family HMM PF06961. | 0.866 |
| leuA | SGO_0911 | SGO_0906 | SGO_0911 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Conserved hypothetical protein; Belongs to the SUA5 family. | 0.719 |
| leuA | leuB | SGO_0906 | SGO_0907 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.999 |
| leuA | leuC | SGO_0906 | SGO_0909 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.999 |
| leuA | leuD | SGO_0906 | SGO_0910 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.999 |
| leuB | SGO_0908 | SGO_0907 | SGO_0908 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Predicted membrane protein of unknown function (DUF1294); Identified by match to protein family HMM PF06961. | 0.885 |
| leuB | SGO_0911 | SGO_0907 | SGO_0911 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Conserved hypothetical protein; Belongs to the SUA5 family. | 0.768 |
| leuB | leuA | SGO_0907 | SGO_0906 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.999 |