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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proWXABC transporter membrane-spanning permease; Identified by match to protein family HMM PF00528; match to protein family HMM PF04069. (506 aa)    
Predicted Functional Partners:
proV
ABC-type proline/glycine betaine transporter; Identified by match to protein family HMM PF00005.
 0.999
potA
Spermidine/putrescine ABC transporter, ATP-binding subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
 
 
 0.663
SGO_1130
Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
  
  
 0.651
msrA
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). Involved in protection against oxidative stress when the bacterium enters the host bloodstream and required for maximal growth under aerobic and anaerobic conditions.
  
  
 0.611
msrA-2
Peptide methionine sulfoxide reductase-like protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.611
SGO_0841
Oxidoreductase; Identified by match to protein family HMM PF08240.
 
    0.585
dltB
Integral membrane protein; Could be involved in the transport of activated D-alanine through the membrane.
      
 0.577
SGO_1037
Glutamine ABC transporter permease and substrate binding protein; Identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726.
     
 0.574
SGO_1727
Amino acid ABC transporter, amino acid-binding/permease protein; Identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726.
     
 0.574
SGO_0273
Zinc-binding oxidoreductase; Identified by match to protein family HMM PF08240.
 
    0.523
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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