close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zmpCZinc metalloproteinase C; Identified by match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07554; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01168. (2597 aa)    
Predicted Functional Partners:
SGO_0945
ABC transporter permease protein; Identified by match to protein family HMM PF02687.
 
    0.849
SGO_1598
Conserved hypothetical protein.
  
     0.714
SGO_1832
Conserved hypothetical protein.
  
     0.704
SGO_1852
Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054.
     
 0.635
sodA
Manganese-dependent superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
  
 0.632
SGO_1163
Iron permease FTR1 family; Identified by match to protein family HMM PF03239.
 
  
 0.629
SGO_2009
Zinc proteinase; Identified by match to protein family HMM PF04228.
      
 0.628
SGO_1136
Putative esterase superfamily; Identified by match to protein family HMM PF00756.
  
     0.609
rpsB
Ribosomal protein S2; Identified by match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family.
      
 0.592
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
  
 0.577
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
Server load: low (36%) [HD]