close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1005Identified by match to protein family HMM PF04816. (229 aa)    
Predicted Functional Partners:
SGO_1006
Conserved hypothetical protein TIGR00486; Identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486.
  
 0.966
SGO_1007
Oxidoreductase, DadA family protein SP1608; Identified by match to protein family HMM PF01266.
       0.781
SGO_1008
Phosphohydrolase (MutT/nudix family protein); Identified by match to protein family HMM PF00293.
       0.757
SGO_2042
Bacterial protein of unknown function (DUF965) superfamily; Identified by match to protein family HMM PF06135; Belongs to the UPF0297 family.
  
     0.737
SGO_1122
Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.725
addA
First chain of major exonuclease RexA; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily.
 
     0.669
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
     0.643
SGO_1003
DNA replication protein DnaD; Identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446.
 
     0.558
recJ
single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644.
       0.522
SGO_0544
Protein of unknown function (DUF448) superfamily; Identified by match to protein family HMM PF04296.
  
   
 0.521
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.