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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1047Conserved hypothetical protein. (424 aa)    
Predicted Functional Partners:
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.781
SGO_1048
Hydrolase, alpha/beta hydrolase fold family; Identified by match to protein family HMM PF00561.
       0.767
ribF
Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family.
       0.720
spxA
Negative regulator of proteolysis; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
       0.537
SGO_1052
Conserved hypothetical protein; Identified by match to protein family HMM PF05256; Belongs to the UPF0223 family.
       0.531
app
Identified by match to protein family HMM PF00459.
       0.531
SGO_1046
Conserved hypothetical protein.
       0.518
SGO_1054
Identified by match to protein family HMM PF01189.
       0.509
SGO_0107
LPXTG cell wall surface protein, collagen binding domain; Identified by match to protein family HMM PF00746; match to protein family HMM PF05737; match to protein family HMM TIGR01167.
  
    0.472
SGO_1045
Transcription regulator BH1216; Identified by match to protein family HMM PF02829; match to protein family HMM PF08279.
       0.445
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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