Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ciaRTranscriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. (224 aa)    
Predicted Functional Partners:
SGO_1073
Sensor protein CiaH; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 0.999
SGO_0484
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 0.998
degP
Serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595.
  
  
 0.994
SGO_1071
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.861
SGO_1180
Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.784
SGO_1416
Putative histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.783
SGO_1074
Conserved hypothetical protein; Identified by match to protein family HMM PF02558.
       0.778
SGO_1907
Sensor protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.763
SGO_0299
Putative histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.712
SGO_0780
Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
 
 
 0.694
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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