Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1086Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. (287 aa)    
Predicted Functional Partners:
SGO_1088
Transcription regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
    0.604
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
       0.602
SGO_1090
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.602
SGO_1087
Exfoliative toxin A; Identified by match to protein family HMM PF03595.
       0.586
SGO_1462
NUDIX domain, putative; Identified by match to protein family HMM PF00293.
  
    0.582
SGO_1480
Ribosomal-protein-alanine acetyltransferase.
  
    0.566
SGO_1083
Sugar ABC transporter, ATP-binding protein SP0846; Identified by match to protein family HMM PF00005.
       0.532
SGO_1084
Sugar ABC transporter permease protein, putative; Identified by match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.
       0.532
SGO_1085
ABC transporter, permease protein; Identified by match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.
       0.532
cysE
Serine O-acetyltransferase; Identified by match to protein family HMM TIGR01172.
       0.455
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
Server load: low (28%) [HD]