STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruRPhosphotransferase system repressor; Identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279. (247 aa)    
Predicted Functional Partners:
fruA
PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
 
  
 0.984
fruB
1-phosphofructokinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.970
pyrR
PyrR bifunctional protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
  
  
 0.667
lacC
Tagatose-6-phosphate kinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR01231; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.630
lacC-2
Tagatose-6-phosphate kinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR01231; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.624
recX
Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family.
      
 0.598
SGO_1037
Glutamine ABC transporter permease and substrate binding protein; Identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726.
      
 0.571
SGO_1114
Protein of unknown function (DUF1149) superfamily; Identified by match to protein family HMM PF06619.
       0.538
SGO_1115
Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762.
       0.538
pyrB
Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
 0.517
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.