Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
fruRPhosphotransferase system repressor; Identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279. (247 aa)    
Predicted Functional Partners:
fruA
PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
 
  
 0.988
fruB
1-phosphofructokinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.986
lacC
Tagatose-6-phosphate kinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR01231; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.710
lacC-2
Tagatose-6-phosphate kinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR01231; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.705
SGO_1114
Protein of unknown function (DUF1149) superfamily; Identified by match to protein family HMM PF06619.
       0.696
SGO_1115
Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762.
       0.696
pcnA
Polynucleotide adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
    0.672
SGO_1118
ABC transporter, ATP-binding protein SP1553; Identified by match to protein family HMM PF00005.
       0.666
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
       0.658
pyrR
PyrR bifunctional protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
  
  
 0.615
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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