STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1122Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. (110 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.898
SGO_1005
Identified by match to protein family HMM PF04816.
  
     0.725
SGO_1862
Alkaline shock protein; Identified by match to protein family HMM PF03780.
 
     0.710
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
  
 0.698
SGO_0544
Protein of unknown function (DUF448) superfamily; Identified by match to protein family HMM PF04296.
  
    0.692
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.649
SGO_2042
Bacterial protein of unknown function (DUF965) superfamily; Identified by match to protein family HMM PF06135; Belongs to the UPF0297 family.
  
     0.645
SGO_1736
Alkaline shock protein; Identified by match to protein family HMM PF03780.
 
     0.555
CtsR
Transcription regulator ctsR; Identified by match to protein family HMM PF05848; Belongs to the CtsR family.
  
     0.546
SGO_1121
Transcription regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.
     
 0.542
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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