SGO_1124 protein (Streptococcus gordonii) - STRING interaction network

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Score

SGO_1124

Cell surface hydrolase; Identified by match to protein family HMM PF06028. (267 aa)

Predicted Functional Partners:

SGO_0057

0.781

dltC

0.771

dltA

0.744

dltB

0.744

SGO_0796

0.640

ffh

0.609

endA

0.604

SGO_0231

0.499

SGO_0730

0.421

Your Current Organism:

Streptococcus gordonii

NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGO_0057	SGO_0231	SGO_0057	SGO_0231	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	Glycerophosphoryl diester phosphodiesterase family protein; Identified by match to protein family HMM PF03009.	0.462
SGO_0057	SGO_0796	SGO_0057	SGO_0796	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	Conserved hypothetical protein; Identified by match to protein family HMM PF00413.	0.450
SGO_0057	SGO_1124	SGO_0057	SGO_1124	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	Cell surface hydrolase; Identified by match to protein family HMM PF06028.	0.781
SGO_0057	dltA	SGO_0057	SGO_0054	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]	0.994
SGO_0057	dltB	SGO_0057	SGO_0055	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	Integral membrane protein; Could be involved in the transport of activated D-alanine through the membrane.	0.999
SGO_0057	dltC	SGO_0057	SGO_0056	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.	0.995
SGO_0231	SGO_0057	SGO_0231	SGO_0057	Glycerophosphoryl diester phosphodiesterase family protein; Identified by match to protein family HMM PF03009.	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	0.462
SGO_0231	SGO_0796	SGO_0231	SGO_0796	Glycerophosphoryl diester phosphodiesterase family protein; Identified by match to protein family HMM PF03009.	Conserved hypothetical protein; Identified by match to protein family HMM PF00413.	0.442
SGO_0231	SGO_1124	SGO_0231	SGO_1124	Glycerophosphoryl diester phosphodiesterase family protein; Identified by match to protein family HMM PF03009.	Cell surface hydrolase; Identified by match to protein family HMM PF06028.	0.499
SGO_0231	dltC	SGO_0231	SGO_0056	Glycerophosphoryl diester phosphodiesterase family protein; Identified by match to protein family HMM PF03009.	D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.	0.557
SGO_0730	SGO_1124	SGO_0730	SGO_1124	Identified by match to protein family HMM PF00149.	Cell surface hydrolase; Identified by match to protein family HMM PF06028.	0.421
SGO_0730	endA	SGO_0730	SGO_0765	Identified by match to protein family HMM PF00149.	DNA-entry nuclease; Identified by match to protein family HMM PF01223.	0.507
SGO_0796	SGO_0057	SGO_0796	SGO_0057	Conserved hypothetical protein; Identified by match to protein family HMM PF00413.	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	0.450
SGO_0796	SGO_0231	SGO_0796	SGO_0231	Conserved hypothetical protein; Identified by match to protein family HMM PF00413.	Glycerophosphoryl diester phosphodiesterase family protein; Identified by match to protein family HMM PF03009.	0.442
SGO_0796	SGO_1124	SGO_0796	SGO_1124	Conserved hypothetical protein; Identified by match to protein family HMM PF00413.	Cell surface hydrolase; Identified by match to protein family HMM PF06028.	0.640
SGO_0796	endA	SGO_0796	SGO_0765	Conserved hypothetical protein; Identified by match to protein family HMM PF00413.	DNA-entry nuclease; Identified by match to protein family HMM PF01223.	0.567
SGO_1124	SGO_0057	SGO_1124	SGO_0057	Cell surface hydrolase; Identified by match to protein family HMM PF06028.	dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.	0.781
SGO_1124	SGO_0231	SGO_1124	SGO_0231	Cell surface hydrolase; Identified by match to protein family HMM PF06028.	Glycerophosphoryl diester phosphodiesterase family protein; Identified by match to protein family HMM PF03009.	0.499
SGO_1124	SGO_0730	SGO_1124	SGO_0730	Cell surface hydrolase; Identified by match to protein family HMM PF06028.	Identified by match to protein family HMM PF00149.	0.421
SGO_1124	SGO_0796	SGO_1124	SGO_0796	Cell surface hydrolase; Identified by match to protein family HMM PF06028.	Conserved hypothetical protein; Identified by match to protein family HMM PF00413.	0.640

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