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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1135Putative esterase superfamily; Identified by match to protein family HMM PF00756. (246 aa)    
Predicted Functional Partners:
SGO_1134
Conserved hypothetical protein.
 
     0.949
SGO_1136
Putative esterase superfamily; Identified by match to protein family HMM PF00756.
 
     0.920
SGO_1137
Formate-nitrate transporter; Identified by match to protein family HMM PF01226.
 
     0.536
zmpB
Zinc metalloproteinase B; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168.
  
     0.526
zmpC
Zinc metalloproteinase C; Identified by match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07554; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01168.
  
     0.503
rgfB
RgfB; Identified by match to protein family HMM PF03372.
  
     0.498
acoA
Acetoin dehydrogenase; Identified by match to protein family HMM PF00676.
       0.453
SGO_1132
Acetoin dehydrogenase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.
       0.431
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.430
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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