| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_0096 | SGO_1261 | SGO_0096 | SGO_1261 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | 0.902 |
| SGO_0096 | apt | SGO_0096 | SGO_1001 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.903 |
| SGO_0096 | gmk | SGO_0096 | SGO_0594 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.900 |
| SGO_0096 | guaA | SGO_0096 | SGO_1120 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.914 |
| SGO_0096 | guaB | SGO_0096 | SGO_0008 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.917 |
| SGO_0096 | guaC | SGO_0096 | SGO_1159 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.906 |
| SGO_0096 | hpt | SGO_0096 | SGO_2134 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
| SGO_0096 | purA | SGO_0096 | SGO_1989 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.906 |
| SGO_0096 | purH | SGO_0096 | SGO_0040 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.903 |
| SGO_0096 | xpt | SGO_0096 | SGO_1158 | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.902 |
| SGO_1261 | SGO_0096 | SGO_1261 | SGO_0096 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | 0.902 |
| SGO_1261 | apt | SGO_1261 | SGO_1001 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.918 |
| SGO_1261 | gmk | SGO_1261 | SGO_0594 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.916 |
| SGO_1261 | guaA | SGO_1261 | SGO_1120 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.906 |
| SGO_1261 | guaB | SGO_1261 | SGO_0008 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.986 |
| SGO_1261 | guaC | SGO_1261 | SGO_1159 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.948 |
| SGO_1261 | hpt | SGO_1261 | SGO_2134 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.917 |
| SGO_1261 | purA | SGO_1261 | SGO_1989 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.438 |
| SGO_1261 | xpt | SGO_1261 | SGO_1158 | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.918 |
| apt | SGO_0096 | SGO_1001 | SGO_0096 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved hypothetical protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. | 0.903 |
STRING v12.5 is now available!
