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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
noxNADH oxidase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992. (458 aa)    
Predicted Functional Partners:
SGO_1007
Oxidoreductase, DadA family protein SP1608; Identified by match to protein family HMM PF01266.
  
 
 0.979
SGO_1438
Metallo-beta-lactamase superfamily protein 4; Identified by match to protein family HMM PF00753.
  
 0.890
sodA
Manganese-dependent superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.853
acdH
Alcohol-acetaldehyde dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
   
 0.717
spxB
Pyruvate oxidase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720; Belongs to the TPP enzyme family.
  
  
 0.689
trxB
Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
     
 0.661
rpmJ
Ribosomal protein L36; Identified by match to protein family HMM PF00444; match to protein family HMM TIGR01022; Belongs to the bacterial ribosomal protein bL36 family.
   
   0.646
SGO_0758
Glutathione peroxidase; Identified by match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
   
  
 0.641
gshAB
Glutamate--cysteine ligase, putative/amino acid ligase, putative; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
  
  
 0.640
spxA
Negative regulator of proteolysis; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
      
 0.639
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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