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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccdA2Cytochrome c-type biogenesis protein; Identified by match to protein family HMM PF02683. (236 aa)    
Predicted Functional Partners:
SGO_1171
Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.
  
 0.986
SGO_1177
Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.
  
 0.970
msrA-2
Peptide methionine sulfoxide reductase-like protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.679
trx-2
Thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family.
  
  
 0.668
SGO_1267
Identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534.
 
  
 0.634
trx-1
Thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM PF08534; match to protein family HMM TIGR01068; Belongs to the thioredoxin family.
  
  
 0.629
SGO_2006
Thioredoxin signature protein; Identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534.
 
  
 0.621
SGO_1175
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00165.
 
   
 0.544
msrA
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). Involved in protection against oxidative stress when the bacterium enters the host bloodstream and required for maximal growth under aerobic and anaerobic conditions.
  
  
 0.539
SGO_1174
Histidine kinase; Identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF02743; match to protein family HMM PF06580.
       0.439
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.