| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_1217 | SGO_1220 | SGO_1217 | SGO_1220 | Lipoprotein, putative. | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.430 |
| SGO_1217 | SGO_1222 | SGO_1217 | SGO_1222 | Lipoprotein, putative. | GTP pyrophosphokinase-like protein; Identified by match to protein family HMM PF04607. | 0.430 |
| SGO_1217 | mutY | SGO_1217 | SGO_1218 | Lipoprotein, putative. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.596 |
| SGO_1217 | ppnK | SGO_1217 | SGO_1221 | Lipoprotein, putative. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.430 |
| SGO_1217 | pta | SGO_1217 | SGO_1219 | Lipoprotein, putative. | Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651. | 0.460 |
| SGO_1220 | SGO_1217 | SGO_1220 | SGO_1217 | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Lipoprotein, putative. | 0.430 |
| SGO_1220 | SGO_1222 | SGO_1220 | SGO_1222 | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTP pyrophosphokinase-like protein; Identified by match to protein family HMM PF04607. | 0.800 |
| SGO_1220 | mutY | SGO_1220 | SGO_1218 | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.608 |
| SGO_1220 | ppnK | SGO_1220 | SGO_1221 | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.811 |
| SGO_1220 | pta | SGO_1220 | SGO_1219 | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651. | 0.749 |
| SGO_1222 | SGO_1217 | SGO_1222 | SGO_1217 | GTP pyrophosphokinase-like protein; Identified by match to protein family HMM PF04607. | Lipoprotein, putative. | 0.430 |
| SGO_1222 | SGO_1220 | SGO_1222 | SGO_1220 | GTP pyrophosphokinase-like protein; Identified by match to protein family HMM PF04607. | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.800 |
| SGO_1222 | mutY | SGO_1222 | SGO_1218 | GTP pyrophosphokinase-like protein; Identified by match to protein family HMM PF04607. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.599 |
| SGO_1222 | ppnK | SGO_1222 | SGO_1221 | GTP pyrophosphokinase-like protein; Identified by match to protein family HMM PF04607. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.847 |
| SGO_1222 | pta | SGO_1222 | SGO_1219 | GTP pyrophosphokinase-like protein; Identified by match to protein family HMM PF04607. | Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651. | 0.750 |
| dnaN | mutM | SGO_0002 | SGO_0715 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.427 |
| dnaN | mutY | SGO_0002 | SGO_1218 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.620 |
| dnaN | recA | SGO_0002 | SGO_2045 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.918 |
| dnaN | xth | SGO_0002 | SGO_1531 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.918 |
| mutM | dnaN | SGO_0715 | SGO_0002 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.427 |
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