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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1226Conserved hypothetical protein; Identified by match to protein family HMM PF08866. (115 aa)    
Predicted Functional Partners:
SGO_1225
Pyridoxal-phosphate dependent aminotransferase; Identified by match to protein family HMM PF00266.
  
 
 0.940
prs
Ribose-phosphate pyrophosphokinase 2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.790
SGO_0501
Uncharacterized ACR, COG1399; Identified by match to protein family HMM PF02620.
  
     0.737
SGO_0005
Membrane protein, putative.
  
     0.720
SGO_1227
Conserved hypothetical protein.
       0.699
SGO_1867
Conserved hypothetical protein; Identified by match to protein family HMM PF06570.
  
     0.692
SGO_1223
Adenylate cyclase; Identified by match to protein family HMM PF01928.
       0.634
SGO_1220
23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
 
     0.551
SGO_0524
HD domain protein; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277.
  
     0.547
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.543
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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