| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_1487 | srtA | SGO_1487 | SGO_1230 | LPXTG cell wall surface protein, Cna protein B-type domain; Identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167. | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | 0.723 |
| SGO_1487 | sspA | SGO_1487 | SGO_0210 | LPXTG cell wall surface protein, Cna protein B-type domain; Identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167. | Identified by match to protein family HMM PF00746; match to protein family HMM PF06696; match to protein family HMM PF08363; match to protein family HMM TIGR01167. | 0.606 |
| abpB | srtA | SGO_0162 | SGO_1230 | Identified by match to protein family HMM PF03577. | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | 0.675 |
| abpB | srtB | SGO_0162 | SGO_2104 | Identified by match to protein family HMM PF03577. | Identified by match to protein family HMM TIGR03064. | 0.468 |
| abpB | sspA | SGO_0162 | SGO_0210 | Identified by match to protein family HMM PF03577. | Identified by match to protein family HMM PF00746; match to protein family HMM PF06696; match to protein family HMM PF08363; match to protein family HMM TIGR01167. | 0.578 |
| gyrA | srtA | SGO_1231 | SGO_1230 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | 0.870 |
| lgt | srtA | SGO_0737 | SGO_1230 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | 0.637 |
| lgt | yidC-2 | SGO_0737 | SGO_0521 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Membrane protein oxaA 2 precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.696 |
| recJ | srtA | SGO_1000 | SGO_1230 | single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | 0.658 |
| scpB | srtA | SGO_1670 | SGO_1230 | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | 0.636 |
| secA | srtA | SGO_0415 | SGO_1230 | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | 0.691 |
| secA | yidC-2 | SGO_0415 | SGO_0521 | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Membrane protein oxaA 2 precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.971 |
| srtA | SGO_1487 | SGO_1230 | SGO_1487 | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | LPXTG cell wall surface protein, Cna protein B-type domain; Identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167. | 0.723 |
| srtA | abpB | SGO_1230 | SGO_0162 | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | Identified by match to protein family HMM PF03577. | 0.675 |
| srtA | gyrA | SGO_1230 | SGO_1231 | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.870 |
| srtA | lgt | SGO_1230 | SGO_0737 | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.637 |
| srtA | recJ | SGO_1230 | SGO_1000 | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.658 |
| srtA | scpB | SGO_1230 | SGO_1670 | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.636 |
| srtA | secA | SGO_1230 | SGO_0415 | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.691 |
| srtA | srtB | SGO_1230 | SGO_2104 | Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. | Identified by match to protein family HMM TIGR03064. | 0.735 |
STRING v12.5 is now available!
