pyrE protein (Streptococcus gordonii) - STRING interaction network

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pyrE

Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (209 aa)

Predicted Functional Partners:

pyrF

0.999

pyrK

0.992

pyrd

0.985

pyrA

0.973

pyrC

0.967

pyrB

0.944

carB

0.922

carA

0.896

SGO_1108

0.889

prs

0.833

Your Current Organism:

Streptococcus gordonii

NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGO_1108	carA	SGO_1108	SGO_1103	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	0.901
SGO_1108	carB	SGO_1108	SGO_1104	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02142; match to protein family HMM PF02222; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369.	0.887
SGO_1108	pyrA	SGO_1108	SGO_0277	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.	0.683
SGO_1108	pyrB	SGO_1108	SGO_1109	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.978
SGO_1108	pyrC	SGO_1108	SGO_1248	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	0.900
SGO_1108	pyrE	SGO_1108	SGO_1253	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.889
SGO_1108	pyrF	SGO_1108	SGO_1254	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.932
SGO_1108	pyrK	SGO_1108	SGO_1256	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).	0.754
SGO_1108	pyrd	SGO_1108	SGO_1255	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	Dihydroorotate dehydrogenase B; Catalyzes the conversion of dihydroorotate to orotate.	0.683
carA	SGO_1108	SGO_1103	SGO_1108	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	0.901
carA	carB	SGO_1103	SGO_1104	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02142; match to protein family HMM PF02222; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369.	0.999
carA	pyrA	SGO_1103	SGO_0277	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.	0.706
carA	pyrB	SGO_1103	SGO_1109	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.999
carA	pyrC	SGO_1103	SGO_1248	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	0.992
carA	pyrE	SGO_1103	SGO_1253	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.896
carA	pyrF	SGO_1103	SGO_1254	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.898
carA	pyrK	SGO_1103	SGO_1256	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).	0.892
carA	pyrd	SGO_1103	SGO_1255	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	Dihydroorotate dehydrogenase B; Catalyzes the conversion of dihydroorotate to orotate.	0.706
carB	SGO_1108	SGO_1104	SGO_1108	Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02142; match to protein family HMM PF02222; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369.	Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.	0.887
carB	carA	SGO_1104	SGO_1103	Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02142; match to protein family HMM PF02222; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369.	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	0.999

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