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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1300Possible NADPH-dependent reductase; Identified by match to protein family HMM PF03358. (128 aa)    
Predicted Functional Partners:
SGO_1301
Conserved hypothetical protein.
       0.661
SGO_0982
Amino acid ABC transporter, amino acid-binding protein; Identified by match to protein family HMM PF00497; Belongs to the bacterial solute-binding protein 3 family.
   
  
 0.610
SGO_1299
Transcriptional regulator MarR family; Identified by match to protein family HMM PF01047.
       0.597
SGO_0985
Amino acid ABC transporter, permease protein SP0711; Identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726.
   
  
 0.594
SGO_0630
Glycerol uptake facilitator protein; Identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.586
msrA
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). Involved in protection against oxidative stress when the bacterium enters the host bloodstream and required for maximal growth under aerobic and anaerobic conditions.
     
 0.580
SGO_0631
Alpha-glycerophosphate oxidase; Identified by match to protein family HMM PF01266.
     
 0.579
SGO_0383
Proton/sodium- glutamate symport protein; Identified by match to protein family HMM PF00375; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
      
 0.576
SGO_0384
Putative carboxylate-amine/thiol ligase.
      
 0.576
SGO_0440
L-iditol 2-dehydrogenase BH3949; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240.
      
 0.576
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.