close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1326Conserved hypothetical protein; Identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906. (206 aa)    
Predicted Functional Partners:
SGO_1327
HAD-superfamily subfamily IIA hydrolase, TIGR01457; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460.
  
    0.867
SGO_1328
Conserved hypothetical protein; Identified by match to protein family HMM PF01643.
 
     0.854
SGO_1329
Oxygen-independent coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.790
SGO_1325
CAAX amino terminal protease family; Identified by match to protein family HMM PF02517.
       0.740
SGO_0501
Uncharacterized ACR, COG1399; Identified by match to protein family HMM PF02620.
  
     0.689
SGO_1330
Transporter; Identified by match to protein family HMM PF00005.
       0.482
SGO_1331
HlyB/MsbA family ABC transporter; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
       0.482
SGO_1324
Hypothetical protein; Identified by Glimmer2; putative.
       0.478
SGO_1046
Conserved hypothetical protein.
  
     0.466
fruA
PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
       0.465
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
Server load: low (38%) [HD]