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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1330Transporter; Identified by match to protein family HMM PF00005. (581 aa)    
Predicted Functional Partners:
SGO_1332
Putative transcription regulator; Identified by match to protein family HMM PF00440.
 
     0.916
ecfA
ABC transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
     
0.889
SGO_1331
HlyB/MsbA family ABC transporter; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
 
   
0.851
SGO_0466
Membrane protein, putative; Identified by match to protein family HMM PF02361.
  
     0.735
SGO_0465
Conserved hypothetical protein; Identified by match to protein family HMM TIGR02185.
 
     0.700
comA
ATP-binding Transport protein ComA; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193.
 
 
  
0.564
SGO_1291
ABC transporter, permease/ATP-binding protein SP1358; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
 
  
0.509
SGO_1329
Oxygen-independent coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
    0.489
SGO_1328
Conserved hypothetical protein; Identified by match to protein family HMM PF01643.
       0.488
SGO_0165
ABC transporter, permease/ATP-binding protein SP2075; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
 
  
0.486
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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