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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1389Conserved hypothetical protein TIGR00147; Identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147. (318 aa)    
Predicted Functional Partners:
SGO_1604
Identified by match to protein family HMM PF01553.
 
  
 0.928
cdsA
Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family.
    
 0.917
SGO_0775
Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534.
   
 
 0.902
SGO_0631
Alpha-glycerophosphate oxidase; Identified by match to protein family HMM PF01266.
    
 0.848
groL
60 kDa chaperonin/groEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 0.831
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); Identified by match to protein family HMM PF01210; match to protein family HMM PF03721; match to protein family HMM PF03807; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.803
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.800
pulA-1
Pullulanase, type I; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; Belongs to the glycosyl hydrolase 13 family.
  
    0.748
SGO_1377
Sulfatase; Identified by match to protein family HMM PF00884.
 
   
 0.573
SGO_1391
Conserved hypothetical protein; Identified by match to protein family HMM PF06177.
       0.542
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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