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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1433Phosphoglycolate phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549. (192 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.800
EzrA
Septation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
       0.603
thiJ
4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein; Identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383.
       0.538
mreB
Cell shape determining protein; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.
       0.529
SGO_1436
Identified by match to protein family HMM PF03601.
       0.510
SGO_0035
Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.
  
  
 0.504
serB
Phosphoserine phosphatase SerB; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488.
  
  
 0.481
SGO_1226
Conserved hypothetical protein; Identified by match to protein family HMM PF08866.
  
     0.432
dinG
DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease.
     
 0.430
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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