| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_0513 | SGO_1538 | SGO_0513 | SGO_1538 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DNA-directed DNA polymerase III, delta'' chain. | 0.427 |
| SGO_0513 | dinG | SGO_0513 | SGO_1437 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. | 0.828 |
| SGO_0513 | dnaN | SGO_0513 | SGO_0002 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.894 |
| SGO_0513 | polI | SGO_0513 | SGO_0145 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.973 |
| SGO_0513 | rpoA | SGO_0513 | SGO_1959 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.991 |
| SGO_0513 | rpoB | SGO_0513 | SGO_1927 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.992 |
| SGO_0513 | rpoC | SGO_0513 | SGO_1926 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DNA-directed RNA polymerase, beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.925 |
| SGO_0513 | rpoZ | SGO_0513 | SGO_0595 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.992 |
| SGO_0513 | topA | SGO_0513 | SGO_1197 | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.740 |
| SGO_1538 | SGO_0513 | SGO_1538 | SGO_0513 | DNA-directed DNA polymerase III, delta'' chain. | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | 0.427 |
| SGO_1538 | dinG | SGO_1538 | SGO_1437 | DNA-directed DNA polymerase III, delta'' chain. | DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. | 0.879 |
| SGO_1538 | dnaN | SGO_1538 | SGO_0002 | DNA-directed DNA polymerase III, delta'' chain. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |
| SGO_1538 | polI | SGO_1538 | SGO_0145 | DNA-directed DNA polymerase III, delta'' chain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.949 |
| SGO_1538 | topA | SGO_1538 | SGO_1197 | DNA-directed DNA polymerase III, delta'' chain. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.542 |
| dinG | SGO_0513 | SGO_1437 | SGO_0513 | DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. | Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455. | 0.828 |
| dinG | SGO_1538 | SGO_1437 | SGO_1538 | DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. | DNA-directed DNA polymerase III, delta'' chain. | 0.879 |
| dinG | dnaN | SGO_1437 | SGO_0002 | DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.881 |
| dinG | gpsA | SGO_1437 | SGO_0164 | DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. | Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); Identified by match to protein family HMM PF01210; match to protein family HMM PF03721; match to protein family HMM PF03807; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.806 |
| dinG | polI | SGO_1437 | SGO_0145 | DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.978 |
| dinG | rpoA | SGO_1437 | SGO_1959 | DnaQ family exonuclease/DinG family helicase, putative; 3'-5' exonuclease. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.978 |