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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1486Beta-galactosidase; Identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168. (2350 aa)    
Predicted Functional Partners:
SGO_0043
Beta-galactosidase; Identified by match to protein family HMM PF01301; match to protein family HMM PF02449; Belongs to the glycosyl hydrolase 35 family.
 
 0.964
galM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
 
 
 0.953
lacE
PTS system, lactose-specific IIBC component; Identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00394; match to protein family HMM TIGR00410; match to protein family HMM TIGR00853.
   
 
 0.914
glcK
Glucokinase; Identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744.
    
 0.906
lacF
PTS system, lactose-specific IIa component; Identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823.
   
 
  0.900
SGO_1771
Conserved hypothetical protein; Identified by match to protein family HMM PF00754.
 
   
 0.855
fucA1
alpha-L-fucosidase; Identified by match to protein family HMM PF01120.
 
   
 0.742
SGO_1770
Glycosyl hydrolase; Identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180.
 
   
 0.702
SGO_1520
PTS system, IIC component; Identified by match to protein family HMM PF03611.
   
  
 0.699
SGO_1769
Protein of unknown function (DUF1237) superfamily; Identified by match to protein family HMM PF06824.
 
     0.695
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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