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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacEPTS system, lactose-specific IIBC component; Identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00394; match to protein family HMM TIGR00410; match to protein family HMM TIGR00853. (568 aa)    
Predicted Functional Partners:
lacF
PTS system, lactose-specific IIa component; Identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823.
 
 0.999
lacG
6-phospho-beta-galactosidase; Identified by match to protein family HMM PF00232; match to protein family HMM TIGR01233; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.997
SGO_1578
PTS system, Lactose/Cellobiose specific IIA subunit; Identified by match to protein family HMM PF02255.
 
 
 0.986
SGO_1645
PTS cellobiose-specific enzyme IIA, putative; Identified by match to protein family HMM PF02255.
 
 
 0.985
SGO_1791
PTS system, Lactose/Cellobiose specific IIA subunit; Identified by match to protein family HMM PF02255.
 
 
 0.984
lacC
Tagatose-6-phosphate kinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR01231; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.932
SGO_1556
Phosphocarrier protein HPr; Identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003.
    
 0.928
SGO_1486
Beta-galactosidase; Identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168.
   
 
 0.914
lacB-2
Galactose-6-phosphate isomerase, LacB subunit; Identified by match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01119.
 
  
 0.911
lacC-2
Tagatose-6-phosphate kinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR01231; match to protein family HMM TIGR03168; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.896
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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