| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_1534 | SGO_1537 | SGO_1534 | SGO_1537 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 0.670 |
| SGO_1534 | SGO_1538 | SGO_1534 | SGO_1538 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | DNA-directed DNA polymerase III, delta'' chain. | 0.652 |
| SGO_1534 | clpP | SGO_1534 | SGO_1632 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.607 |
| SGO_1534 | nth | SGO_1534 | SGO_1533 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.591 |
| SGO_1534 | ogt | SGO_1534 | SGO_1535 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.800 |
| SGO_1534 | rpoA | SGO_1534 | SGO_1959 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.563 |
| SGO_1534 | rpoD | SGO_1534 | SGO_1273 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.557 |
| SGO_1534 | rsmI | SGO_1534 | SGO_1536 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | Conserved hypothetical protein TIGR00096; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.670 |
| SGO_1534 | spxA | SGO_1534 | SGO_1051 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | Negative regulator of proteolysis; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.756 |
| SGO_1534 | tmk | SGO_1534 | SGO_1539 | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.652 |
| SGO_1537 | SGO_1534 | SGO_1537 | SGO_1534 | Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | 0.670 |
| SGO_1537 | SGO_1538 | SGO_1537 | SGO_1538 | Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | DNA-directed DNA polymerase III, delta'' chain. | 0.868 |
| SGO_1537 | nth | SGO_1537 | SGO_1533 | Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.454 |
| SGO_1537 | ogt | SGO_1537 | SGO_1535 | Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.670 |
| SGO_1537 | rsmI | SGO_1537 | SGO_1536 | Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Conserved hypothetical protein TIGR00096; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.812 |
| SGO_1537 | tmk | SGO_1537 | SGO_1539 | Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.841 |
| SGO_1538 | SGO_1534 | SGO_1538 | SGO_1534 | DNA-directed DNA polymerase III, delta'' chain. | ArsC family; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; Belongs to the ArsC family. | 0.652 |
| SGO_1538 | SGO_1537 | SGO_1538 | SGO_1537 | DNA-directed DNA polymerase III, delta'' chain. | Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 0.868 |
| SGO_1538 | nth | SGO_1538 | SGO_1533 | DNA-directed DNA polymerase III, delta'' chain. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.518 |
| SGO_1538 | ogt | SGO_1538 | SGO_1535 | DNA-directed DNA polymerase III, delta'' chain. | methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.652 |