STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgP-1Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (798 aa)    
Predicted Functional Partners:
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.993
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.992
glgD
Glucose-1-phosphate adenylyltransferase, GlgD subunit; Identified by match to protein family HMM TIGR02092.
 
 
 0.991
malQ
4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217.
 
 
 0.976
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
  
 0.958
pulA-2
Pullulanase, type I; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; Belongs to the glycosyl hydrolase 13 family.
  
 
 0.940
pulA-1
Pullulanase, type I; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; Belongs to the glycosyl hydrolase 13 family.
  
 
 0.940
SGO_1351
Neopullulanase alpha amylase domain; Identified by match to protein family HMM PF00128; match to protein family HMM PF02903; Belongs to the glycosyl hydrolase 13 family.
  
 0.927
SGO_1075
Alpha-amylase precursor; Identified by match to protein family HMM PF00128.
  
 0.921
manB
Phosphomannomutase; Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.
  
 
 0.917
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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