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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1575Competence protein CoiA; Identified by match to protein family HMM PF06054. (317 aa)    
Predicted Functional Partners:
SGO_1917
Conserved hypothetical protein.
  
     0.752
SGO_0852
TPR domain protein; Identified by similarity to GB:AAO81340.1; match to protein family HMM PF00515.
  
     0.728
EzrA
Septation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.717
mecA
Adapter protein mec; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
 
     0.698
SGO_0888
Conserved hypothetical protein; Identified by match to protein family HMM PF07949.
  
     0.681
comYC
ComYC competence protein; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532.
  
  
 0.635
comX
ComX.
      
 0.623
SGO_0539
ABC transporter, permease protein; Identified by match to protein family HMM PF05975.
  
     0.598
comB
Transport protein ComB; Identified by match to protein family HMM TIGR01000.
      
 0.570
ptcC
PTS system, IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
       0.538
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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