| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| arcA | arcB | SGO_1593 | SGO_1592 | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.999 |
| arcA | arcC | SGO_1593 | SGO_1591 | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | Carbamate kinase; Identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746; Belongs to the carbamate kinase family. | 0.988 |
| arcA | arcR | SGO_1593 | SGO_1588 | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | Arginine repressor; In the presence of arginine, coactivates the transcription of the arcABDC operon, with other regulatory proteins such as ArcR and CcpA. | 0.671 |
| arcA | argG | SGO_1593 | SGO_0175 | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.914 |
| arcA | argH | SGO_1593 | SGO_0176 | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838. | 0.945 |
| arcA | argJ | SGO_1593 | SGO_1568 | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.453 |
| arcA | argR-2 | SGO_1593 | SGO_0697 | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | Transcription regulator; Regulates arginine biosynthesis genes. | 0.618 |
| arcA | queA | SGO_1593 | SGO_1587 | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity). Seems to have a role in modulation of ADS (arginine deiminase system) gene expression, perhaps exerting a negative effect on the translation of arc regulatory proteins. | 0.461 |
| arcB | arcA | SGO_1592 | SGO_1593 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | 0.999 |
| arcB | arcC | SGO_1592 | SGO_1591 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Carbamate kinase; Identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746; Belongs to the carbamate kinase family. | 0.998 |
| arcB | arcR | SGO_1592 | SGO_1588 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Arginine repressor; In the presence of arginine, coactivates the transcription of the arcABDC operon, with other regulatory proteins such as ArcR and CcpA. | 0.822 |
| arcB | argB | SGO_1592 | SGO_1567 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.929 |
| arcB | argC | SGO_1592 | SGO_1569 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.924 |
| arcB | argG | SGO_1592 | SGO_0175 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.991 |
| arcB | argH | SGO_1592 | SGO_0176 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838. | 0.951 |
| arcB | argJ | SGO_1592 | SGO_1568 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.992 |
| arcB | argR-2 | SGO_1592 | SGO_0697 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Transcription regulator; Regulates arginine biosynthesis genes. | 0.787 |
| arcB | queA | SGO_1592 | SGO_1587 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity). Seems to have a role in modulation of ADS (arginine deiminase system) gene expression, perhaps exerting a negative effect on the translation of arc regulatory proteins. | 0.640 |
| arcC | arcA | SGO_1591 | SGO_1593 | Carbamate kinase; Identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746; Belongs to the carbamate kinase family. | Arginine deiminase; Identified by similarity to GB:AAN65255.1; match to protein family HMM PF02274; match to protein family HMM TIGR01078; Belongs to the arginine deiminase family. | 0.988 |
| arcC | arcB | SGO_1591 | SGO_1592 | Carbamate kinase; Identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746; Belongs to the carbamate kinase family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.998 |